Table of Contents

Ion Channels, from Fantasy to Fact in Fifty Years1.- Specific Channel Types.- Gramicidin Channels: Versatile Tools.- Voltage-Gated Ion Channels.- Voltage-Gated Potassium Channels.- BKCa-Channel Structure and Function.- Voltage-Gated Sodium Channels.- Calcium Channels.- Chloride Transporting CLC Proteins1.- Ligand-Gated Ion Channels: Permeation and Activation1.- Mechanosensitive Channels.- TRP Channels.- Ion Channels in Epithelial Cells.- Theoretical Approaches.- Poisson–Nernst–Planck Theory of Ion Permeation Through Biological Channels.- A Mesoscopic–Microscopic Perspective on Ion Channel Permeation Energetics: The Semi-Microscopic Approach1.- Brownian Dynamics: Simulation for Ion Channel Permeation1.- Molecular Dynamics Simulation Approaches to K Channels.- Emerging Technologies.- Patch-Clamp Technologies for Ion Channel Research.- Gated Ion Channel-Based Biosensor Device.- Signal Processing Based on Hidden Markov Models for Extracting Small Channel Currents.